As a traveler that drives to every assignment, I have just about mastered the highway tricks.
I have a large truck, so along with being filled to capacity with all my belongings, I have everything I could need for any unexpected stops. I also really hate to stop between gas stations or when I need food, so being a guy, I keep my trusty empty gatoraid bottle should my Red Bull work its way through my system (you ever tried urinating while passing a semi at 65 on the interstate?). FYI, they do also make a female urinal should the situation arise, but I would suggest using it in a non-moving auto.
I also have a stereo with CD player, HD radio, terrestrial radio, Sirius sat. radio, a USB and aux input (for MP3 player) and a DVD player. You should never watch DVD's while driving!! That said, a few episodes of Seinfeld at 3AM can be just the thing to keep you awake on a lonely interstate.
That is also a fine time to be driving. Certainly I can understand that not all females wish to be out on the road at those hours, but if you are stopping at large truck stops with tons of people around, you should be fine. I also dont want to start a whole NRA debate here, but I do prefer to carry protection with me if I am driving at night.
You should also carry a AAA card and cell phone should you have any trouble while on the road. Most basic plans are less than $50 a year which is a small price to pay for insuring you have resources available should you have problems. Also consider the time of year in which you will be traveling. Blankets and warm clothes are needed for winter travel and plenty of water for warmer weather.
I had a two-part column in Healthcare Traveler Magazine last year that detailed more on making cross country trips. If you'd like to take a look, the first can be found here in part 1 or the second in part 2.
Hope these give you some ideas on surviving those long trips.
David Morrison
Author: Travel Nurse's Bible
david@travelnursesbible.com